Readthrough domain
WebMay 26, 2024 · ARTDeco processes NGS data (e.g., RNA-seq) to characterize the features of readthrough transcription genome-wide. This includes the identification of genes that exhibit transcription downstream of their 3′ ends (readthrough genes), genes that are transcribed as a result of readthrough transcription from upstream genes (read-in genes), as well as … WebThe readthrough domain itself can be subdivided into a 67 globular NN-terminal portion ( RTD) and an unstructured C-terminal portion ( C RTD) that undergoes 68 proteolytic …
Readthrough domain
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WebBeet western yellows luteovirus (BWYV) mutants devoid of the readthrough domain (RTD) did not bind to Buchnera GroEL, demonstrating that the RTD (and not the highly conserved CP) contains the determinants for GroEL binding. In vivo studies showed that virions of these BWYV mutants were significantly less persistent in the aphid hemolymph than ... WebParticularly, higher levels were detected for B-domain variants (n=20) than for variants in other domains (n=25). Studies on plasma from six hemophilia A patients with PTC, …
WebJan 7, 2024 · The capsid protein readthrough domain (CP-RTD), being a minor component of icosahedral virions, mediates persistent, circulative aphid transmission of luteoviruses. Likewise, benyviruses encode the CP-RTD exposed at one end of the rod-like helical particle, which serves for the virus transmission by soil fungal zoospores. ... WebNov 25, 2024 · The advantage of having the unfractionated long RNAs from FLEP-seq data enabled us to distinguish and categorize the RNA intermediates into four groups: readthrough transcripts, 5′ cleavage products, 3′ cleavage products, and poly(A) transcripts (Fig. 1a; Additional file 1, Fig. S2).Take DRM2 (AT2G33830) as an example (Fig. 1b, upper …
WebMar 1, 2024 · Furthermore, the readthrough domain was not required for systemic infection of plants, but did influence the accumulation of virus in infected plants. The 17-kDa protein is required for the ... WebProteins encoded by open reading frames (ORF) 3, 4, and 5 of the barley yellow dwarf luteovirus genome are translated from a single subgenomic RNA. The structural proteins are encoded by ORF 3 (coat protein) and ORF 5 (readthrough domain) and contain undefined domains that regulate the movement of virus through aphid vectors. The biological …
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WebOct 26, 2024 · The N-terminal portion of the viral readthrough domain (N RTD) has been implicated as a key determinant of aphid transmission in each of these genera. … citya belvia toulouse locationWebIt can be formed as a result of premature stop codon readthrough, complex phenomenon enabling stop codon circumvention. ... QUATERNARY STRUCTURE CATALYTIC COFACTOR BINDING DOMAIN α11 α2 DOMAIN αβ α10 * α1 α9 β6 β12 β12 α14 αA α13 α3 i α4 β13 BRIDGING β0 DOMAIN Figure Figure10.10.Predicted Predictedtertiary tertiaryand ... citya besancondickson county middle schoolWebA fraction of the coat protein (CP) subunits in virions of members of the family Luteoviridae contain a C-terminal extension called the readthrough domain (RTD). The RTD is necessary for persistent aphid transmission, but its role is unknown. It has been reported to be required for virion stability … dickson county middle school dickson tnWebOct 1, 1999 · The complete nucleotide sequence (6043 nt) of RNA 1 from Potato mop-top virus (PMTV-Sw), the type member of the genus Pomovirus, was determined. The first (5′-terminal) open reading frame (ORF 1) encodes a predicted protein of 148 kDa. ORF 2 extends through the opal stop codon of ORF 1 producing a predicted readthrough protein … city abilene tx building permitsWebApr 10, 2024 · The N-terminal portion of the viral readthrough domain (N RTD) has been implicated as a key determinant of aphid transmission in each of these genera. Sequence … citya belvia immobilier toulouseWebVIRION. Non-enveloped, spherical virion about 23 nm in diameter with T=3 icosahedral symmetry composed of 180 CP proteins, with some percentage containing a readthrough domain (RTD) extension located on the particle's surface.. GENOME. Monopartite, linear, ssRNA(+) genome of 5.3-5.7 kb in size with a VPg bound at the 5' end. There is no poly(A) … city abbotsford careers