Web3 nov. 2024 · The ITPR3 gene encodes IP3 receptor type 3, which releases intracellular Ca(2+) from the endoplasmic reticulum into the cytoplasm upon binding of the IP3 ligand … Webgroups based on ITPR3 mRNA expression levels. The first group consisted of 39 out of 370 patients (10.5%) with elevated ITPR3 expression (z>1.0 as the cut-off). The remaining 331 patients (z<1.0) were grouped as normal ITPR3 expression. Overall and disease-free 5-year survival curves for each group were plotted in GraphPad Prism. Animal studies
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Web1 jan. 2024 · ITPR3 is partially concentrated at ER-mitochondrial contact sites in a liver cancer cell line. Super-resoluton images of a HepG2 cell expressing a GFP-tagged … WebERCC1(核苷酸切除修复交叉互补组1-Excision Repair Cross Complementing group 1):是核酸外切修复家族中重要成员,为NER系统关键成员,参与DNA链切割和损伤识别.ERCC1基因也是第一个克隆到的人类DNA损伤修复基因.所有肿瘤细胞中都有ERCC1表达,而且表达水平差异很大。 sharp slicer
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WebInositol 1,4,5-trisphosphate receptor type 3 (ITPR3) is overexpressed in cholangiocarcinoma and its expression correlates with S100 calcium-binding protein … Web5 jun. 2014 · In this study, we examined tear secretion in mice lacking the inositol 1,4,5-trisphosphate receptor (IP 3 R) types 2 and 3 ( Itpr2−/−;Itpr3−/− double-knockout mice). We found that tear secretion in both the parasympathetic and sympathetic pathways was abolished in Itpr2−/−;Itpr3−/− mice. Intracellular Ca 2+ elevation in lacrimal ... Web22 feb. 2024 · Lentiviral transfer plasmids pLCS-ITPR3-1 and pLCS-ITPR3-2 (GenScript, USA) contained a lentiCRISPRv2 backbone and single above-mentioned oligos cloned … sharps linen cartridge about